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Experimental and Theoretical Studies of Linked Biochemical Processes PDF By:Martin Luke Rennie Published on 2016 by Proteins are a class of biological macromolecules that participate in intricate chemical processes such as binding of small molecules, self-assembly, and catalysis. Often multiple chemical processes are coupled giving rise to complex biological phenomena. Characterization of the coupling between chemical processes is essential to providing an understanding of biology at the molecular level. This study is concerned with development of analytic treatments of these biochemical linkages. In particular several models of linked biochemical systems are developed. In order to apply biochemical linkage models to protein systems, experimental measurements are used to determine the model parameters. Standard parameter estimation techniques employed in biophysics and biochemistry are of limited utility here owing to the complexity of the models. Instead the robust Markov Chain Monte ...